The Outcome of Endoscopic Surgery on Patients With Sinonasal Inverted Papilloma

AUTHORS

Soheila Nikakhlagh 1 , Sana Taiebi 1 , Leila Sistani Karampur 1 , Ghasem Neici 2 , Nader Saki 3 , *

1 Hearing and Speech Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran

2 Radiology Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran

3 Cancer Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran

How to Cite: Nikakhlagh S, Taiebi S, Sistani Karampur L, Neici G, Saki N. The Outcome of Endoscopic Surgery on Patients With Sinonasal Inverted Papilloma, Jentashapir J Cell Mol Biol. Online ahead of Print ; 6(4):30658. doi: 10.17795/jjhr-30658.

ARTICLE INFORMATION

Jentashapir Journal of Health Research: 6 (4); 30658
Published Online: August 28, 2015
Article Type: Research Article
Received: June 8, 2015
Accepted: July 11, 2015
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Abstract

Background: Inverted papillomas comprise 0.5% - 4% of benign epithelial nasal tumors that arise primarily from the lateral nasal wall. The main characteristic is their tendency to recur and the risk of malignant transformation.

Objectives: The aim of this study was to report on our experience in the treatment of these lesions, especially through the endoscopic approach, and the outcome of the patients.

Patients and Methods: This is a retrospective report describing 38 patients who underwent endoscopic excision or open surgery from March 2001 to March 2012. The patients were studied by consideration of their age, gender, origin of lesion, presenting symptoms, radiological studies, clinical staging, method of treatment, follow up, surgical outcome, tumor recurrence and associated malignancy. The mean follow-up was 47.84 months.

Results: There were 30 males and eight females, and the mean age was 49.76 years ranging from 18 to 78 years. The most common clinical symptoms were unilateral nasal obstruction (94.7%) and rhinorrhea (36.84%). Disease recurrence rate was 5.3%. Endonasal endoscopic resection was performed for 32 patients (84.2%), combined approaches were used for five patients (13.2%) and external approach was only done for one patient. The most common involvement location was the maxillary sinus (89%). The ethmoid sinus and the lateral nasal wall were involved in 68% and 55.2% of the cases, respectively. Malignant transformation was observed in two patients (5.3%).

Conclusions: Long-term follow up of inverted papilloma is necessary for early detection of recurrence and to allow for surgical salvage. Surgeons experience plays a decisive role in the selection of an appropriate method.

Keywords

Papilloma, Inverted Endoscopic Operative Open Operative

© 2015, School of Medicine, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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