Jentashapir Journal of Health Research

Published by: Kowsar

Determination of Survival Rate and Its Effective Factors in Pediatric Leukemia in Hamadan Province During Years 2007 to 2016

Mostafa Eghbalian 1 , Negar Assadi Sajadi 1 , Ghodratollah Roshanaei 2 , * , Sasan Amiri 3 , Hossein Esfahani 4 and Mohsen Ahmadi 1
Authors Information
1 Hamadan University of Medical Sciences and Health Services, Hamadan, Iran
2 Modeling of Non-Communicable Diseases Research Center, Hamadan University of Medical Sciences and Health Services, Hamadan, Iran
3 Department of Medical-Surgical Nursing, Faculty of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran
4 Pediatric Hematology and Oncology, Hamadan University of Medical Sciences, Hamadan, Iran
Article information
  • Jentashapir Journal of Health Research: April 2018, 9 (2); e79335
  • Published Online: September 1, 2018
  • Article Type: Research Article
  • Received: May 19, 2018
  • Accepted: August 12, 2018
  • DOI: 10.5812/jjhr.79335

To Cite: Eghbalian M, Assadi Sajadi N, Roshanaei G, Amiri S, Esfahani H, et al. Determination of Survival Rate and Its Effective Factors in Pediatric Leukemia in Hamadan Province During Years 2007 to 2016, Jentashapir J Health Res. 2018 ; 9(2):e79335. doi: 10.5812/jjhr.79335.

Copyright © 2018, Jentashapir Journal of Health Research. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Methods
3. Results
4. Discussion
  • 1. Ismael AI, Hassan JG. Five years survival of children with leukemia in Basra Oncology Center. Cancer Biol Ther Oncol. 2017;1(1).
  • 2. Mousavi SM, Gouya MM, Ramazani R, Davanlou M, Hajsadeghi N, Seddighi Z. Cancer incidence and mortality in Iran. Ann Oncol. 2009;20(3):556-63. doi: 10.1093/annonc/mdn642. [PubMed: 19073863].
  • 3. Alebouyeh M. Current status of pediatric oncology in Iran. Arch Iranian Med. 2003;6(3):160-2.
  • 4. Parkin DM, Stiller CA, Draper GJ, Bieber CA. The international incidence of childhood cancer. Int J Cancer. 1988;42(4):511-20. [PubMed: 3170025].
  • 5. Pession A, Dama E, Rondelli R, Magnani C, De Rosa M, Locatelli F, et al. Survival of children with cancer in Italy, 1989-98. A report from the hospital based registry of the Italian Association of Paediatric Haematology and Oncology (AIEOP). Eur J Cancer. 2008;44(9):1282-9. doi: 10.1016/j.ejca.2008.03.020. [PubMed: 18430564].
  • 6. Belson M, Kingsley B, Holmes A. Risk factors for acute leukemia in children: a review. Environ Health Perspect. 2007;115(1):138-45. doi: 10.1289/ehp.9023. [PubMed: 17366834]. [PubMed Central: PMC1817663].
  • 7. Conter V, Sala A, Chiesa R, Citterio M, Biondi A. Acute lymphoblastic leukemia. Orphanet Encyclopedia. 2004.
  • 8. Ebrahimi A, Kamarehie B, Asgari G, Seid Mohammadi A, Roshanaei G. [Drinking water corrosivity and sediment in the distribution network of Kuhdasht, Iran]. Health Sys Res. 2012;8(3):480-6. Persian.
  • 9. Karimi M, Mehrabani D, Yarmohammadi H, Jahromi FS. The prevalence of signs and symptoms of childhood leukemia and lymphoma in Fars Province, Southern Iran. Cancer Detect Prev. 2008;32(2):178-83. doi: 10.1016/j.cdp.2008.06.001. [PubMed: 18632219].
  • 10. Leukemia CL. The leukemia and lymphoma society. 2008. Available from:
  • 11. Gatta G, Luksch R, Coleman MP, Corazziari I; Eurocare Working Group. Survival from acute non-lymphocytic leukaemia (ANLL) and chronic myeloid leukaemia (CML) in European children since 1978: a population-based study. Eur J Cancer. 2001;37(6):695-702. [PubMed: 11311643].
  • 12. Pui CH, Relling MV, Downing JR. Acute lymphoblastic leukemia. N Engl J Med. 2004;350(15):1535-48. doi: 10.1056/NEJMra023001. [PubMed: 15071128].
  • 13. Siegel R, Desantis C, Jemal A. Colorectal cancer statistics, 2014. CA Cancer J Clin. 2014;64(2):104-17. doi: 10.3322/caac.21220. [PubMed: 24639052].
  • 14. Klein JP, Moeschberger ML. Survival analysis: techniques for censored and truncated data. New York: Springer Science & Business Media; 2006.
  • 15. Parvareh M, Khanjani N. The survival of childhood leukemia and its related factors in Kerman, Iran. Iran J Health Sci. 2015;3(4):24-32.
  • 16. Zareifar S, Almasi-Hashiani A, Karimi M, Tabatabaee SH, Ghiasvand R. [Five-year survival rate of pediatric leukemia and its determinants]. Koomesh. 2012;14(1):13-9. Persian.
  • 17. Bahrami M, Moshkani MR, Aalam Samimi M. [Effective factors on survival time of the leukemic patients and estimating the mean of survival time by expectation and maximization algorithm and Monte Carlo Markov Chains Simulation Method]. J Isfahan Med Sch. 2007;25(84):49-57. Persian.
  • 18. Mousavinasab SN, Yazdani Cherati J, Karami H, Khaksar S. [Risk factors influencing the survival of pediatric acute leukemia using competing risk model]. J Mazandaran Univ Med Sci. 2015;24(121):31-8. Persian.
  • 19. Pastore G, Viscomi S, Gerov GL, Terracini B, Madon E, Magnani C. Population-based survival after childhood lymphoblastic leukaemia in time periods corresponding to specific clinical trials from 1979 to 1998--a report from the Childhood Cancer Registry of Piedmont (Italy). Eur J Cancer. 2003;39(7):952-60. [PubMed: 12706364].
  • 20. Hazar V, Karasu GT, Uygun V, Akcan M, Kupesiz A, Yesilipek A. Childhood acute lymphoblastic leukemia in Turkey: factors influencing treatment and outcome: a single center experience. J Pediatr Hematol Oncol. 2010;32(8):e317-22. doi: 10.1097/MPH.0b013e3181ed163c. [PubMed: 20930649].
  • 21. Swaminathan R, Rama R, Shanta V. Childhood cancers in Chennai, India, 1990-2001: incidence and survival. Int J Cancer. 2008;122(11):2607-11. doi: 10.1002/ijc.23428. [PubMed: 18324630].
  • 22. Hashemi A, Manochehri Naieni M, Eslami Z, Bahrami Ahmadi A, Kheirandish M, Rafieyan M. [Evaluation of prognostic and predictive factors in pediatric acute lymphoblatic leukemia patients admitted to Shahid Sadoughi Hospital]. J Shahid Sadoughi Univ Med Sci. 2009;16(5):14-9. Persian.
  • 23. Hussein H, Sidhom I, Naga SA, Amin M, Ebied E, Khairy A, et al. Outcome and prognostic factors of acute lymphoblastic leukemia in children at the National Cancer Institute, Egypt. J Pediatr Hematol Oncol. 2004;26(8):507-14. [PubMed: 15284589].
  • 24. Bajel A, George B, Mathews V, Viswabandya A, Kavitha ML, Srivastava A, et al. Treatment of children with acute lymphoblastic leukemia in India using a BFM protocol. Pediatr Blood Cancer. 2008;51(5):621-5. doi: 10.1002/pbc.21671. [PubMed: 18688848].
  • 25. Tsurusawa M, Yumura-Yagi K, Ohara A, Hara J, Katano N, Tsuchida M, et al. Survival outcome after the first central nervous system relapse in children with acute lymphoblastic leukemia: a retrospective analysis of 79 patients in a joint program involving the experience of three Japanese study groups. Int J Hematol. 2007;85(1):36-40. doi: 10.1532/IJH97.06085. [PubMed: 17261500].
  • 26. Arellano ML, Langston A, Winton E, Flowers CR, Waller EK. Treatment of relapsed acute leukemia after allogeneic transplantation: a single center experience. Biol Blood Marrow Transplant. 2007;13(1):116-23. doi: 10.1016/j.bbmt.2006.09.005. [PubMed: 17222760].
  • 27. Zeidler L, Zimmermann M, Moricke A, Meissner B, Bartels D, Tschan C, et al. Low platelet counts after induction therapy for childhood acute lymphoblastic leukemia are strongly associated with poor early response to treatment as measured by minimal residual disease and are prognostic for treatment outcome. Haematologica. 2012;97(3):402-9. doi: 10.3324/haematol.2011.045229. [PubMed: 22058224]. [PubMed Central: PMC3291595].

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