Jentashapir Journal of Health Research

Published by: Kowsar

Sildenafil Citrate Can Reduce Pathological Post-obstructive Diuresis in a Rat Model ofBilateral Ureteral Obstruction

Hayat Mombeini 1 , Mohammad Reza Dadfar 2 , Dinyar Khazaeli 3 , * and Bahman Jalili-Anarakie 4
Authors Information
1 Professor of Urology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
2 Assistant Professor of Urology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
3 Assistant Professor of Urology, Fellow of Robotic Surgeries, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
4 Resident of Urology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
Article information
  • Jentashapir Journal of Health Research: June 2017, 8 (3); e58776
  • Published Online: June 30, 2017
  • Article Type: Research Article
  • Received: March 30, 2017
  • Accepted: April 29, 2017
  • DOI: 10.5812/jjhr.58776

To Cite: Mombeini H, Dadfar M R, Khazaeli D, Jalili-Anarakie B. Sildenafil Citrate Can Reduce Pathological Post-obstructive Diuresis in a Rat Model ofBilateral Ureteral Obstruction, Jentashapir J Health Res. 2017 ;8(3):e58776. doi: 10.5812/jjhr.58776.

Abstract
Copyright © 2017, Jentashapir Journal of Health Research. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Methods
3. Results
4. Discussion
Acknowledgements
References
  • 1. Yang S, Qian H, Song C, Xia Y, Cheng F, Zhang C. Emergency ureteroscopic treatment for upper urinary tract calculi obstruction associated with acute renal failure: feasible or not? J Endourol. 2010;24(11):1721-4. doi: 10.1089/end.2009.0420. [PubMed: 20958134].
  • 2. Verkman AS, Shi LB, Frigeri A, Hasegawa H, Farinas J, Mitra A, et al. Structure and function of kidney water channels. Kidney Int. 1995;48(4):1069-81. [PubMed: 8569068].
  • 3. Nielsen S, Agre P. The aquaporin family of water channels in kidney. Kidney Int. 1995;48(4):1057-68. [PubMed: 8569067].
  • 4. Jensen AM, Li C, Praetorius HA, Norregaard R, Frische S, Knepper MA, et al. Angiotensin II mediates downregulation of aquaporin water channels and key renal sodium transporters in response to urinary tract obstruction. Am J Physiol Renal Physiol. 2006;291(5):F1021-32. doi: 10.1152/ajprenal.00387.2005. [PubMed: 16757730].
  • 5. Jensen AM, Bae EH, Fenton RA, Norregaard R, Nielsen S, Kim SW, et al. Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstruction. Am J Physiol Renal Physiol. 2009;296(1):F127-34. doi: 10.1152/ajprenal.90479.2008. [PubMed: 18971210].
  • 6. Li C, Wang W, Kwon TH, Isikay L, Wen JG, Marples D, et al. Downregulation of AQP1, -2, and -3 after ureteral obstruction is associated with a long-term urine-concentrating defect. Am J Physiol Renal Physiol. 2001;281(1):F163-71. doi: 10.1152/ajprenal.2001.281.1.F163. [PubMed: 11399657].
  • 7. Kim SW, Cho SH, Oh BS, Yeum CH, Choi KC, Ahn KY, et al. Diminished renal expression of aquaporin water channels in rats with experimental bilateral ureteral obstruction. J Am Soc Nephrol. 2001;12(10):2019-28. [PubMed: 11562400].
  • 8. Murer L, Addabbo F, Carmosino M, Procino G, Tamma G, Montini G, et al. Selective decrease in urinary aquaporin 2 and increase in prostaglandin E2 excretion is associated with postobstructive polyuria in human congenital hydronephrosis. J Am Soc Nephrol. 2004;15(10):2705-12. doi: 10.1097/01.ASN.0000139689.94776.7A. [PubMed: 15466275].
  • 9. Frokiaer J, Marples D, Knepper MA, Nielsen S. Bilateral ureteral obstruction downregulates expression of vasopressin-sensitive AQP-2 water channel in rat kidney. Am J Physiol. 1996;270(4 Pt 2):F657-68. doi: 10.1152/ajprenal.1996.270.4.F657. [PubMed: 8967344].
  • 10. Bouley R, Pastor-Soler N, Cohen O, McLaughlin M, Breton S, Brown D. Stimulation of AQP2 membrane insertion in renal epithelial cells in vitro and in vivo by the cGMP phosphodiesterase inhibitor sildenafil citrate (Viagra). Am J Physiol Renal Physiol. 2005;288(6):F1103-12. doi: 10.1152/ajprenal.00337.2004. [PubMed: 15644488].
  • 11. Gulmi FA, Matthews GJ, Marion D, von Lutterotti N, Vaughan ED. Volume expansion enhances the recovery of renal function and prolongs the diuresis and natriuresis after release of bilateral ureteral obstruction: a possible role for atrial natriuretic peptide. J Urol. 1995;153(4):1276-83. [PubMed: 7869528].
  • 12. Li C, Wang W, Kwon TH, Knepper MA, Nielsen S, Frokiaer J. Altered expression of major renal Na transporters in rats with unilateral ureteral obstruction. Am J Physiol Renal Physiol. 2003;284(1):F155-66. doi: 10.1152/ajprenal.00272.2002. [PubMed: 12388400].
  • 13. Norregaard R, Jensen BL, Li C, Wang W, Knepper MA, Nielsen S, et al. COX-2 inhibition prevents downregulation of key renal water and sodium transport proteins in response to bilateral ureteral obstruction. Am J Physiol Renal Physiol. 2005;289(2):F322-33. doi: 10.1152/ajprenal.00061.2005. [PubMed: 15840770].
  • 14. Murphy GP, Scott WW. The renal hemodynamic response to acute and chronic ureteral occlusions. J Urol. 1966;95(5):636-57. [PubMed: 5935525].
  • 15. Reyes AA, Robertson G, Klahr S. Role of vasopressin in rats with bilateral ureteral obstruction. Proc Soc Exp Biol Med. 1991;197(1):49-55. [PubMed: 2020670].
  • 16. Vaughan EJ, Marion D, Poppas DP, Felsen D. Pathophysiology of unilateral ureteral obstruction: studies from Charlottesville to New York. J Urol. 2004;172(6 Pt 2):2563-9. [PubMed: 15538209].
  • 17. Kauker ML, Zawada ET. Post-obstruction diuresis: influence of renal prostaglandins. Nephron. 1992;60(3):281-5. [PubMed: 1565180].
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments