Jentashapir Journal of Health Research

Published by: Kowsar

Study of Spermatogenesis in Wistar Adult Rats Administrated to Long Term of Ruta Graveolens

Mahshid Bazrafkan 1 and Aligholi Sobhani 2 , *
Authors Information
1 Department of Anatomy, School of Medicine, Alborz University of Medical Sciences, Karaj, IR Iran
2 Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, IR Iran
Article information
  • Jentashapir Journal of Health Research: August 01, 2014, 5 (4); e21870
  • Published Online: July 18, 2014
  • Article Type: Research Article
  • Received: August 28, 2013
  • Revised: January 16, 2014
  • Accepted: April 22, 2014
  • DOI: 10.17795/jjhr-21870

To Cite: Bazrafkan M, Sobhani A. Study of Spermatogenesis in Wistar Adult Rats Administrated to Long Term of Ruta Graveolens, Jentashapir J Health Res. 2014 ; 5(4):e21870. doi: 10.17795/jjhr-21870.

Abstract
Copyright © 2014, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Sailani MR, Moeini H. Effect of Ruta graveolens and Cannabis sativa alcoholic extract on spermatogenesis in the adult wistar male rats. Indian J Urol. 2007; 23(3): 257-60[DOI][PubMed]
  • 2. Bone W, Jones AR, Morin C, Nieschlag E, Cooper TG. Susceptibility of glycolytic enzyme activity and motility of spermatozoa from rat, mouse, and human to inhibition by proven and putative chlorinated antifertility compounds in vitro. J Androl. 2001; 22(3): 464-70[PubMed]
  • 3. Rahim F, Saki G, Bazrafkan M. Effect of Alcohol Extracts of the Ruta graveolens L. On the Count, Motility and in vitro Fertilization Capacity of Rat's Sperm. Asian J. Plant Sci. 2010; 9(1): 63-6[DOI]
  • 4. De Feo V, De Simone F, Senatore F. Potential allelochemicals from the essential oil of Ruta graveolens. Phytochemistry. 2002; 61(5): 573-8[PubMed]
  • 5. de Freitas TG, Augusto PM, Montanari T. Effect of Ruta graveolens L. on pregnant mice. Contraception. 2005; 71(1): 74-7[DOI][PubMed]
  • 6. Gutierrez-Pajares JL, Zuniga L, Pino J. Ruta graveolens aqueous extract retards mouse preimplantation embryo development. Reprod Toxicol. 2003; 17(6): 667-72[PubMed]
  • 7. Nakhai LA, Mohammadirad A, Yasa N, Minaie B, Nikfar S, Ghazanfari G, et al. Benefits of Zataria multiflora Boiss in Experimental Model of Mouse Inflammatory Bowel Disease. Evid Based Complement Alternat Med. 2007; 4(1): 43-50[DOI][PubMed]
  • 8. Ojala T, Remes S, Haansuu P, Vuorela H, Hiltunen R, Haahtela K, et al. Antimicrobial activity of some coumarin containing herbal plants growing in Finland. J Ethnopharmacol. 2000; 73(1-2): 299-305[PubMed]
  • 9. Oliva A, Meepagala KM, Wedge DE, Harries D, Hale AL, Aliotta G, et al. Natural fungicides from Ruta graveolens L. leaves, including a new quinolone alkaloid. J Agric Food Chem. 2003; 51(4): 890-6[DOI][PubMed]
  • 10. Meepagala KM, Schrader KK, Wedge DE, Duke SO. Algicidal and antifungal compounds from the roots of Ruta graveolens and synthesis of their analogs. Phytochemistry. 2005; 66(22): 2689-95[DOI][PubMed]
  • 11. Raghav SK, Gupta B, Agrawal C, Goswami K, Das HR. Anti-inflammatory effect of Ruta graveolens L. in murine macrophage cells. J Ethnopharmacol. 2006; 104(1-2): 234-9[DOI]
  • 12. Chiu KW, Fung AY. The cardiovascular effects of green beans (Phaseolus aureus), common rue (Ruta graveolens), and kelp (Laminaria japonica) in rats. Gen Pharmacol. 1997; 29(5): 859-62[PubMed]
  • 13. Sallal AKJ, Alkofahi A. Inhibition of the hemolytic activities of snake and scorpion venoms in vitro with plant extracts. J Biomed Lett. 1996; 53: 211-5
  • 14. el Agraa SE, el Badwi SM, Adam SE. Preliminary observations on experimental Ruta graveolens toxicosis in Nubian goats. Trop Anim Health Prod. 2002; 34(4): 271-81[PubMed]
  • 15. Hadis M, Lulu M, Mekonnen Y, Asfaw T. Field trials on the repellent activity of four plant products against mainly Mansonia population in western Ethiopia. Phytother Res. 2003; 17(3): 202-5[DOI][PubMed]
  • 16. Hale AL, Meepagala KM, Oliva A, Aliotta G, Duke SO. Phytotoxins from the leaves of Ruta graveolens. J Agric Food Chem. 2004; 52(11): 3345-9[DOI][PubMed]
  • 17. Gravot A, Larbat R, Hehn A, Lievre K, Gontier E, Goergen JL, et al. Cinnamic acid 4-hydroxylase mechanism-based inactivation by psoralen derivatives: cloning and characterization of a C4H from a psoralen producing plant-Ruta graveolens-exhibiting low sensitivity to psoralen inactivation. Arch Biochem Biophys. 2004; 422(1): 71-80[PubMed]
  • 18. Ciganda C, Laborde A. Herbal infusions used for induced abortion. J Toxicol Clin Toxicol. 2003; 41(3): 235-9[PubMed]
  • 19. Diawaraa MM, Chavez KJ, Simpleman D, Williams DE, Franklin MR, Hoyer PB. The psoralens adversely affect reproductive function in male wistar rats. Reprod Toxicol. 2001; 15(2): 137-44[PubMed]
  • 20. Khouri NA, El-Akawi Z. Antiandrogenic activity of Ruta graveolens L in male Albino rats with emphasis on sexual and aggressive behavior. Neuro Endocrinol Lett. 2005; 26(6): 823-9[PubMed]
  • 21. Ahmadi A. The effect of aqueous extract of Sodab on spermatogenesis in immature rats. M.Sc.thesis,the Scientific Research Center of Poonak 2005;
  • 22. Harat ZN, Sadeghi MR, Sadeghipour HR, Kamalinejad M, Eshraghian MR. Immobilization effect of Ruta graveolens L. on human sperm: a new hope for male contraception. J Ethnopharmacol. 2008; 115(1): 36-41[DOI][PubMed]
  • 23. Bazrafkan M, Panahi M, Saki G, Ahangarpou A, Zaeimzadeh N. Effect of Aqueous Extract of Ruta graveolens on Spermatogenesis of Adult Rats. Ijp. 2010; 6(6): 926-9[DOI]
  • 24. Movassaghi S, Saki G, Javadnia F, Panahi M, Mahmoudi M, Rhim F. Effects of methyl-beta-cyclodextrin and cholesterol on cryosurvival of spermatozoa from C57BL/6 mouse. Pak J Biol Sci. 2009; 12(1): 19-25[PubMed]
  • 25. Hjollund NH, Bonde JP, Henriksen TB, Giwercman A, Olsen J. Job strain and male fertility. Epidemiology. 2004; 15(1): 114-7[DOI][PubMed]
  • 26. Pook M, Tuschen-Caffier B, Kubek J, Schill WB, Krause W. Personality, coping and sperm count. Andrologia. 2005; 37(1): 29-35[DOI][PubMed]
  • 27. Ozawa N, Goda N, Makino N, Yamaguchi T, Yoshimura Y, Suematsu M. Leydig cell-derived heme oxygenase-1 regulates apoptosis of premeiotic germ cells in response to stress. J Clin Invest. 2002; 109(4): 457-67[DOI][PubMed]
  • 28. Rethy B, Zupko I, Minorics R, Hohmann J, Ocsovszki I, Falkay G. Investigation of cytotoxic activity on human cancer cell lines of arborinine and furanoacridones isolated from Ruta graveolens. Planta Med. 2007; 73(1): 41-8[DOI][PubMed]
  • 29. Petrunkina AM, Harrison RA, Hebel M, Weitze KF, Topfer-Petersen E. Role of quinine-sensitive ion channels in volume regulation in boar and bull spermatozoa. Reproduction. 2001; 122(2): 327-36[PubMed]
  • 30. Saki G, Rahim F, Ghavamizadeh B, Jafaee A, Kadkhodaee M. The Effect of Oxamate on Fertilization Capacity of Mouse Sperm in vitro. ijp. 2009; 5(2): 178-80[DOI]
  • 31. Ramesh B, Pugalendi KV. Antihyperglycemic effect of umbelliferone in streptozotocin-diabetic rats. J Med Food. 2006; 9(4): 562-6[DOI][PubMed]
  • 32. Chowdhury AK, Steinberger E. Effect of 5alpha reduced androgens on sex accessory organs, initiation and maintenance of spermatogenesis in the rat. Biol Reprod. 1975; 12(5): 609-17[PubMed]
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